The Life of God in the Soul of Man was instrumental in George Whitefield’s conversion, and was also a turning point in John Newton's Christian growth.

Scougal produced a number of works in his brief life while a pastor and professor of divinity at King's College, Aberdeen. His greatest production is by consensus, The Life of God In The Soul of Man, which was originally written to a friend to explain Christianity and give spiritual counsel. This short treatise displays unusual perception and maturity for one so young. In fact, this work was almost universally well-spoken of by the leaders of the Great Awakening, including George Whitefield, who said he never really understood what true religion was till he had digested Scougal's treatise.

In addition to his literary productions, Henry Scougal was also noted for his piety and his clear grasp of scripture, aided in turn by his proficiency in Latin, Hebrew, Greek, and some of the cognate oriental languages. Taken out of the world at the young age of twenty-eight by tuberculosis, perhaps the words preached at his funeral service most aptly characterize the man, for there it was declared of Henry Scougal that - "he truly lived much in a few years and died an old man in eight and twenty years.”

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